Through games of Sunday, April 25, 2021
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Trinity (Texas) (15) | 25-4 | 612 | 2 |
| 2 | Washington U. (5) | 22-3 | 586 | 1 |
| 3 | Webster (2) | 25-5 | 547 | 4 |
| 4 | Salisbury | 16-3 | 526 | 3 |
| 5 | Marietta (1) | 21-3 | 495 | 6 |
| 6 | Washington and Jefferson (1) | 27-1 | 489 | 7 |
| 7 | Aurora | 24-4 | 448 | 5 |
| 8 | UW-Whitewater | 21-4 | 436 | 8 |
| 9 | North Central (Ill.) | 23-5 | 423 | 11 |
| 10 | Babson | 8-2 | 360 | 10 |
| 11 | Rowan | 15-3 | 323 | 16 |
| 12 | North Carolina Wesleyan | 26-6 | 303 | 9 |
| 13 | Adrian | 24-6 | 284 | 18 |
| 14 | Chapman (1) | 4-1 | 273 | 12 |
| 15 | Shenandoah | 22-7 | 253 | 15 |
| 16 | Berry | 32-9 | 235 | 13 |
| 17 | Randolph-Macon | 20-8 | 201 | 14 |
| 18 | Coe | 25-4 | 198 | 20 |
| 19 | Wheaton (Mass.) | 8-2 | 180 | 21 |
| 20 | Centenary (La.) | 29-7 | 177 | 19 |
| 21 | Eastern Connecticut | 21-4 | 118 | 23 |
| 22 | Southern Maine | 16-8 | 99 | 22 |
| 23 | William Paterson | 20-5 | 92 | 24 |
| 24 | Cal Lutheran | 3-5 | 60 | 17 |
| 25 | Wooster | 17-5 | 50 | 25 |
Dropped out: none.
Others receiving votes: Oswego State 48, Birmingham Southern 47, Augustana (Ill.) 46, St. John Fisher 42, Cortland 41, Gustavus Adolphus 34, Penn St.-Abington 14, La Roche 14, Beloit 11, St. Thomas (Minn.) 9, Johns Hopkins 8, Piedmont 7, Christopher Newport 7, Louisiana College 6, UW-Stevens Point 6, Denison 5, SUNY Brockport 4, Spalding 3, Wittenberg 2.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.