Regional rankings from Week One (April 24, 2019)
| Central | In-Division Record | Overall Record | |
| 1 | Washington U. in St. Louis | 26-5-6 | 26-5-1 |
| 2 | Spalding | 26-7 | 26-7 |
| 3 | Coe | 27-2 | 28-2 |
| 4 | Webster | 24-8 | 24-8 |
| 5 | North Central (Illinois) | 23-7 | 23-7 |
| 6 | North Park | 16-11 | 16-11 |
| 7 | Luther | 18-13 | 18-14 |
| Mid-Atlantic | In-Division Record | Overall Record | |
| 1 | Rowan | 24-6 | 24-7 |
| 2 | The College of New Jersey | 25-5 | 25-5 |
| 3 | Johns Hopkins | 24-9 | 25-9 |
| 4 | Kean | 25-11 | 25-11 |
| 5 | Penn State Harrisburg | 23-10-1 | 23-10-1 |
| 6 | Misericordia | 24-10 | 24-10 |
| 7 | Ramapo | 19-10 | 19-10 |
| 8 | William Patterson | 20-13 | 20-13 |
| 9 | Hood | 23-9-1 | 23-9-1 |
| 10 | Alvernia | 22-11-2 | 22-11-2 |
| 11 | Dickinson | 22-10 | 22-10 |
| 12 | Franklin and Marshall | 22-12 | 22-12 |
| Mideast | In-Division Record | Overall Record | |
| 1 | Denison | 27-3 | 27-3 |
| 2 | Case Western Reserve | 20-11 | 20-11 |
| 3 | Heidelberg | 22-10 | 22-10 |
| 4 | Baldwin Wallace | 20-9 | 20-9 |
| 5 | Adrian | 22-6 | 22-6 |
| 6 | Wooster | 18-8 | 18-8 |
| 7 | Washington and Jefferson | 21-8 | 22-9 |
| 8 | La Roche | 17-10 | 17-10 |
| 9 | John Carroll | 20-10 | 20-10 |
| 10 | Rose-Hulman | 20-9 | 20-9 |
| 11 | DePauw | 19-11 | 19-11 |
| Midwest | In-Division Record | Overall Record | |
| 1 | Concordia Chicago | 26-2 | 26-2 |
| 2 | Wisconsin-Whitewater | 20-5 | 20-6 |
| 3 | Benedictine (Illinois) | 17-9 | 17-9 |
| 4 | Wisconsin-La Crosse | 16-10 | 16-10 |
| 5 | St. Thomas (Minnesota) | 18-8 | 16-8 |
| 6 | Aurora | 21-6 | 21-6 |
| 7 | St. Scholastica | 17-7 | 17-8 |
| 8 | St. John's (Minnesota) | 24-9 | 24-9 |
| New England | In-Division Record | Overall Record | |
| 1 | Babson | 25-4 | 25-4 |
| 2 | Southern Maine | 23-5 | 23-5 |
| 3 | Wheaton (Massachusetts) | 25-6 | 25-6 |
| 4 | Trinity (Connecticut) | 22-5 | 23-5 |
| 5 | Massachusetts Boston | 19-10 | 19-10 |
| 6 | Endicott | 18-13 | 18-13 |
| 7 | Western New England | 18-10 | 18-10 |
| 8 | Mitchell | 24-5 | 25-6 |
| 9 | Williams | 16-7 | 16-7 |
| 10 | Salve Regina | 16-13 | 16-13 |
| 11 | Amherst | 13-10 | 14-10 |
| 12 | MIT | 15-13-1 | 15-13-1 |
| 13 | Eastern Connecticut State | 15-13 | 16-13 |
| New York | In-Division Record | Overall Record | |
| 1 | SUNY Cortland | 26-9-1 | 26-9-1 |
| 2 | St. John Fisher | 22-10 | 22-10 |
| 3 | Ithaca | 22-7 | 22-7 |
| 4 | Farmingdale State | 26-6 | 26-6 |
| 5 | Oswego State | 22-11 | 22-11 |
| 6 | New York University | 19-10 | 19-10 |
| 7 | Merchant Marine | 25-8 | 25-9 |
| 8 | Clarkson | 14-11 | 14-11 |
| South | In-Division Record | Overall Record | |
| 1 | Salisbury | 26-6-1 | 26-6-1 |
| 2 | Birmingham Southern | 29-11 | 29-11 |
| 3 | Christopher Newport | 27-4 | 27-4 |
| 4 | LaGrange | 24-8 | 26-9 |
| 5 | Piedmont | 25-7 | 29-8 |
| 6 | Hendrix | 28-11 | 28-12 |
| 7 | Rhodes | 22-16 | 23-17 |
| 8 | Berry | 27-13 | 27-13 |
| West | In-Division Record | Overall Record | |
| 1 | Chapman | 24-9 | 24-9 |
| 2 | Trinity (Texas) | 29-8 | 30-9 |
| 3 | Texas Lutheran | 27-8 | 27-8 |
| 4 | La Verne | 25-9 | 25-9 |
| 5 | Concordia University Texas | 27-9 | 27-9 |
| 6 | Cal Lutheran | 23-11 | 23-11 |
| 7 | Occidental | 23-11 | 23-11 |