Regional rankings from Week Two, through Games May 5, 2019
| Central | In-Division Record | Overall Record | |
| 1 | Washington U. | 31-5-1 | 31-5-1 |
| 2 | Webster | 29-10 | 29-10 |
| 3 | Coe | 31-3 | 32-3 |
| 4 | Spalding | 29-10 | 29-10 |
| 5 | North Central (Ill.) | 28-11 | 28-11 |
| 6 | Augustana | 26-13-1 | 26-13-1 |
| 7 | Millikin | 21-18 | 21-18 |
| Mid-Atlantic | In-Division Record | Overall Record | |
| 1 | TCNJ | 30-9 | 30-9 |
| 2 | Rowan | 30-9 | 30-10 |
| 3 | Johns Hopkins | 28-11 | 29-11 |
| 4 | Kean | 29-14 | 29-14 |
| 5 | Penn State-Harrisburg | 31-11-1 | 31-11-1 |
| 6 | Ramapo | 25-13 | 25-13 |
| 7 | Misericordia | 31-10 | 31-10 |
| 8 | Alvernia | 27-14-2 | 27-14-2 |
| 9 | Franklin and Marshall | 27-15 | 27-15 |
| 10 | William Paterson | 25-15 | 25-15 |
| 11 | Swarthmore | 24-12 | 24-12 |
| 12 | Keystone | 22-12 | 22-13 |
| Mideast | In-Division Record | Overall Record | |
| 1 | Denison | 34-6 | 34-6 |
| 2 | Heidelberg | 28-11 | 28-11 |
| 3 | Baldwin Wallace | 25-13 | 25-13 |
| 4 | Case Western Reserve | 22-13 | 22-13 |
| 5 | Adrian | 32-7 | 32-7 |
| 6 | Wooster | 24-10 | 24-10 |
| 7 | Washington and Jefferson | 28-10 | 29-11 |
| 8 | La Roche | 27-13 | 27-13 |
| 9 | Rose-Hulman | 25-10 | 25-10 |
| 10 | Wabash | 21-17 | 21-17 |
| 11 | Ohio Northern | 20-16 | 21-16 |
| Midwest | In-Division Record | Overall Record | |
| 1 | Concordia Chicago | 33-5 | 33-5 |
| 2 | Wisconsin-Whitewater | 31-8 | 31-9 |
| 3 | Wisconsin-La Crosse | 25-13 | 25-13 |
| 4 | Aurora | 30-8 | 30-8 |
| 5 | Gustavus Adolphus | 22-10 | 23-11 |
| 6 | St. John's (Minnesota) | 28-11 | 28-11 |
| 7 | Benedictine (Illinois) | 23-15 | 23-15 |
| 8 | St. Olaf | 25-13 | 26-13 |
| New England | In-Division Record | Overall Record | |
| 1 | Southern Maine | 32-5 | 32-5 |
| 2 | Babson | 31-6 | 31-6 |
| 3 | Trinity (Conn.) | 25-7 | 26-7 |
| 4 | Wheaton (Mass.) | 27-10 | 27-10 |
| 5 | Massachusetts Boston | 26-11 | 26-11 |
| 6 | Mitchell | 33-6 | 34-7 |
| 7 | Tufts | 25-8 | 26-8 |
| 8 | MIT | 21-16-1 | 21-16-1 |
| 9 | Western New England | 23-13 | 23-13 |
| 10 | Salve Regina | 24-15 | 24-15 |
| 11 | Williams | 23-9 | 23-9 |
| 12 | Endicott | 22-18 | 22-18 |
| 13 | Eastern Connecticut | 21-16 | 22-16 |
| New York | In-Division Record | Overall Record | |
| 1 | Cortland | 31-10-1 | 31-10-1 |
| 2 | Ithaca | 28-7 | 28-7 |
| 3 | St. John Fisher | 26-11 | 26-11 |
| 4 | Farmingdale State | 30-7 | 30-7 |
| 5 | Oswego State | 28-12 | 28-12 |
| 6 | New York University | 26-12 | 26-12 |
| 7 | Merchant Marine | 28-8 | 28-9 |
| 8 | Rochester | 24-14 | 24-14 |
| South | In-Division Record | Overall Record | |
| 1 | Birmingham-Southern | 33-11 | 33-11 |
| 2 | Salisbury | 34-8-1 | 34-8-1 |
| 3 | Christopher Newport | 33-6 | 33-6 |
| 4 | LaGrange | 28-8 | 30-9 |
| 5 | Hendrix | 30-13 | 30-14 |
| 6 | Piedmont | 25-9 | 29-10 |
| 7 | Rhodes | 25-17 | 26-18 |
| 8 | Randolph-Macon | 25-8-1 | 25-8-1 |
| West | In-Division Record | Overall Record | |
| 1 | Chapman | 30-9 | 30-9 |
| 2 | Trinity (Texas) | 33-9 | 34-10 |
| 3 | Texas Lutheran | 31-12 | 31-12 |
| 4 | La Verne | 29-11 | 29-11 |
| 5 | Occidental | 28-12 | 28-12 |
| 6 | Concordia (Texas) | 32-10 | 32-10 |
| 7 | Cal Lutheran | 26-14 | 26-14 |