Through games of Sunday, March 6, 2022:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Cortland (7) | 7-2 | 585 | 1 |
| 2 | Marietta (8) | 3-1 | 582 | 2 |
| 3 | Birmingham-Southern (4) | 10-2 | 566 | 3 |
| 4 | North Central (Ill.) (5) | 7-0 | 557 | 7 |
| 5 | Salisbury | 7-4 | 457 | 8 |
| 6 | Eastern Connecticut | 3-0 | 426 | 9 |
| 7 | Lynchburg | 10-1 | 423 | 15 |
| 8 | Webster | 5-1 | 373 | 12 |
| 9 | Texas-Dallas | 12-1 | 368 | 16 |
| 10 | Rowan | 3-1 | 353 | 11 |
| 11 | Johns Hopkins | 4-3 | 346 | 5 |
| 12 | Wheaton (Mass.) | 1-0 | 345 | 14 |
| 13 | UW-Whitewater | 2-2 | 326 | 6 |
| 14 | Adrian | 4-3 | 291 | 4 |
| 15 | LaGrange (1) | 12-1 | 248 | 21 |
| 16 | Aurora | 2-1 | 242 | 10 |
| 17 | Trinity (Texas) | 5-5 | 202 | 17 |
| 18 | Shenandoah | 10-3 | 193 | 18 |
| 19 | Southern Maine | 1-2 | 189 | 13 |
| 20 | Cal Lutheran | 12-2 | 187 | 23 |
| 21 | Kean | 11-1 | 182 | 24 |
| 22 | Denison | 3-0 | 179 | 25 |
| 23 | Washington and Jefferson | 4-2 | 115 | 22 |
| 24 | Chapman | 6-4 | 90 | 19 |
| 25 | East Texas Baptist | 14-3 | 53 | rv |
Dropped out: No. 20 St. John Fisher
Others receiving votes: Baldwin Wallace 52, William Paterson 48, Oswego State 26, Piedmont 16, N.C. Wesleyan 16, Millikin 16, Loras 15, Babson 14, UW-Stevens Point 12, Tufts 12, Hendrix 11, Berry 10, Washington (Mo.) 9, Augustana 9, Case Western Reserve 9, Christopher Newport 9, Wabash 8, Pacific Lutheran 6, Rochester 6, UW-La Crosse 4, Salve Regina 4, Marymount 1, St. John Fisher 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.