Through games of Sunday, April 3, 2022:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Marietta (24) | 19-3 | 622 | 1 |
| 2 | Eastern Connecticut | 15-2 | 565 | 3 |
| 3 | Birmingham-Southern (1) | 21-7 | 541 | 2 |
| 4 | LaGrange | 20-3 | 516 | 4 |
| 5 | Lynchburg | 20-5 | 496 | 5 |
| 6 | Cortland | 18-6 | 472 | 6 |
| 7 | Rowan | 15-4 | 461 | 7 |
| 8 | Baldwin Wallace | 17-3 | 424 | 9 |
| 9 | North Central (Ill.) | 16-5 | 375 | 8 |
| 10 | UW-Whitewater | 11-4 | 350 | 10 |
| 11 | Salisbury | 17-7 | 340 | 11 |
| 12 | Webster | 14-5 | 336 | 12 |
| 13 | Texas-Dallas | 20-6 | 265 | 13 |
| 14 | Kean | 19-4 | 259 | 15 |
| 15 | Tufts | 14-3 | 228 | 18 |
| 16 | Oswego State | 13-3 | 198 | 20 |
| 17 | Arcadia | 20-3 | 196 | 24 |
| 18 | Loras | 21-3 | 195 | 16 |
| 19 | Aurora | 11-4 | 173 | 17 |
| 20 | UW-Stevens Point | 11-2 | 141 | 25 |
| 21 | Trinity (Texas) | 16-7 | 131 | 22 |
| 22 | Chapman | 17-7 | 122 | 19 |
| 23 | Shenandoah | 17-8-1 | 102 | 14 |
| 24 | Christopher Newport | 18-6 | 95 | rv |
| 25 | La Verne | 19-4-1 | 93 | rv |
Dropped out: No. 21 Denison, No. 23 Cal Lutheran.
Others receiving votes: Roger Williams 57, Denison 46, Pomona-Pitzer 43, Hendrix 41, Rochester 40, Randolph-Macon 30, Bethel (Minn.) 27, Pacific Lutheran 23, Cal Lutheran 23, East Texas Baptist 14, Brockport 13, Adrian 11, Washington & Jefferson 11, Berry 8, Mass.-Boston 7, Ithaca 2, Rhodes 2, Texas Lutheran 2, Babson 2, Immaculata 1, Scranton 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.