Through games of Sunday, April 24, 2022:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Marietta (25) | 31-3 | 625 | 1 |
| 2 | Eastern Connecticut | 27-3 | 571 | 2 |
| 3 | Birmingham-Southern | 31-7 | 563 | 3 |
| 4 | LaGrange | 30-5 | 535 | 4 |
| 5 | Cortland | 26-7 | 497 | 6 |
| 6 | Lynchburg | 29-7 | 489 | 5 |
| 7 | Rowan | 26-6 | 480 | 7 |
| 8 | Arcadia | 31-5 | 401 | 9 |
| 9 | UW-Whitewater | 23-6 | 387 | 10 |
| 10 | Webster | 24-5 | 381 | 11 |
| 11 | Salisbury | 24-8 | 364 | 8 |
| 12 | Baldwin Wallace | 26-6 | 342 | 13 |
| 13 | North Central (Ill.) | 25-8 | 321 | 12 |
| 14 | Trinity (Texas) | 26-8 | 298 | 15 |
| 15 | UW-Stevens Point | 24-4 | 264 | 16 |
| 16 | Kean | 29-7 | 255 | 14 |
| 17 | Pomona-Pitzer | 26-5 | 207 | 19 |
| 18 | Oswego State | 21-7 | 172 | 20 |
| 19 | La Verne | 25-7-1 | 165 | 18 |
| 20 | Aurora | 24-7 | 154 | 21 |
| 21 | Shenandoah | 26-9-1 | 117 | 24 |
| 22 | Christopher Newport | 24-10 | 90 | rv |
| 23 | Texas-Dallas | 26-10 | 85 | 17 |
| 24 | Chapman | 25-9 | 70 | rv |
| 25 | Denison | 20-7 | 65 | rv |
Dropped out: No. 22 Rochester, No. 23 Tufts, No. 25 Texas Lutheran.
Others receiving votes: Endicott 44, Rochester 44, Roger Williams 37, Benedictine 24, Tufts 14, Bethel (Minn.) 12, East Texas Baptist 10, Washington & Jefferson 10, Brockport 8, Wheaton (Mass.) 6, Texas Lutheran 5, Cal Lutheran 4, Ithaca 3, Loras 2, Randolph-Macon 2, Scranton 2, Babson 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.