Records are final records in 2021, Previous rankings are from the final 2021 D3baseball.com/NCBWA Top 25
The first Top 25 of the regular season will be posted March 1, 2022
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Salisbury (24) | 34-4 | 622 | 1 |
| 2 | Cortland | 33-9 | 580 | 4 |
| 3 | Marietta | 38-6 | 548 | 8 |
| 4 | Johns Hopkins | 15-6 | 473 | 10 |
| 5 | Adrian | 37-10 | 433 | 5 |
| 6 | UW-Whitewater | 40-7 | 418 | 9 |
| 7 | Birmingham-Southern | 28-16 | 394 | 16 |
| 8 | Aurora | 38-8 | 378 | 14 |
| 9 | Washington U. (1) | 34-6 | 334 | 3 |
| 10 | Eastern Connecticut | 32-8 | 330 | 19 |
| 11 | Chapman | 15-6 | 327 | 22 |
| 12 | Rowan | 29-6 | 326 | 7 |
| 13 | Southern Maine | 34-11 | 299 | 12 |
| 14 | Webster | 37-8 | 284 | 11 |
| 15 | Trinity (Texas) | 28-9 | 262 | 17 |
| 16 | Wheaton (Mass.) | 21-7 | 254 | 6 |
| 17 | Washington and Jefferson | 37-3 | 237 | 13 |
| 18 | Pacific | 34-15 | 211 | 21 |
| 19 | North Carolina Wesleyan | 33-10 | 180 | 24 |
| 20 | North Central (Ill.) | 38-9 | 165 | 18 |
| 21 | Denison | 27-13 | 145 | 15 |
| 22 | Shenandoah | 31-11 | 100 | rv |
| 23 | St. John Fisher | 31-7 | 95 | 23 |
| 24 | Tufts | 15-8 | 88 | rv |
| 25 | Texas-Dallas | 30-12 | 82 | rv |
Others receiving votes: Lynchburg 71, Misericordia 71, Texas Lutheran 60, Northwestern (Minn.) 51, Keystone 35, York (Pa.) 32, Oswego 27, LaGrange 21, Millikin 16, Coe 15, Rhodes 15, Penn St.-Behrend 11, Mount Union 11, Salve Regina 11, Rochester 9, UW-La Crosse 8, Wooster 7, Centenary (La.) 7, Saint John's (Minn.) 7, Montclair St. 6, Piedmont 6, Gustavus Adolphus 5, UW-Stevens Point 4, William Paterson 4, Transylvania 4, Cal Lutheran 4, Randolph-Macon 3, Rose-Hulman 3, Scranton 3, UW-Oshkosh 3, Babson 2, East Texas Baptist 2, Baldwin Wallace 1, Pacific Lutheran 1, Swarthmore 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.