Through games of May 1, 2022
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Marietta (25) | 35-3 | 625 | 1 |
| 2 | Eastern Connecticut | 32-3 | 591 | 2 |
| 3 | Birmingham-Southern | 36-8 | 556 | 3 |
| 4 | Rowan | 30-6 | 533 | 7 |
| 5 | LaGrange | 32-6 | 499 | 4 |
| 6 | Lynchburg | 32-8 | 464 | 6 |
| 7 | UW-Whitewater | 27-6 | 456 | 9 |
| 8 | Webster | 30-5 | 447 | 10 |
| 9 | Arcadia | 34-6 | 397 | 8 |
| 10 | Salisbury | 26-8 | 376 | 11 |
| 11 | North Central (Ill.) | 28-8 | 363 | 13 |
| 12 | Trinity (Texas) | 29-8 | 349 | 14 |
| 13 | Cortland | 27-10 | 328 | 5 |
| 14 | Oswego State | 24-8 | 290 | 18 |
| 15 | Baldwin Wallace | 28-9 | 247 | 12 |
| 16 | UW-Stevens Point | 24-6 | 234 | 15 |
| 17 | La Verne | 29-7-1 | 206 | 19 |
| 18 | Aurora | 26-7 | 199 | 20 |
| 19 | Chapman | 28-9 | 170 | 24 |
| 20 | Denison | 25-8 | 145 | 25 |
| 21 | Shenandoah | 29-10-1 | 132 | 21 |
| 22 | Endicott | 31-5 | 115 | rv |
| 23 | Kean | 29-11 | 75 | 16 |
| 24 | Pomona-Pitzer | 26-8 | 65 | 17 |
| 25 | Montclair State | 30-9 | 50 | rv |
Dropped out: No. 22 Christopher Newport, No. 23 Texas-Dallas.
Others receiving votes: Christopher Newport 44, Brockport 34, Rochester 25, Wheaton (Mass.) 16, Texas-Dallas 15, Roger Williams 10, Washington & Jefferson 8, Loras 7, Salve Regina 4, Cal Lutheran 3, East Texas Baptist 3, Ithaca 3, Texas Lutheran 3, Tufts 2, Randolph-Macon 2, Stevens 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.