Through games of Sunday, March 13, 2022:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Marietta (14) | 9-2 | 610 | 2 |
| 2 | Cortland (10) | 10-3 | 588 | 1 |
| 3 | Birmingham-Southern | 11-4 | 498 | 3 |
| 4 | Eastern Connecticut (1) | 4-0 | 487 | 6 |
| 5 | North Central (Ill.) | 8-2 | 478 | 4 |
| 6 | Lynchburg | 12-2 | 471 | 7 |
| 7 | Texas-Dallas | 15-2 | 453 | 9 |
| 8 | Salisbury | 10-5 | 444 | 5 |
| 9 | Rowan | 5-1 | 432 | 10 |
| 10 | Webster | 6-2 | 409 | 8 |
| 11 | Wheaton (Mass.) | 2-0 | 397 | 12 |
| 12 | LaGrange | 14-1 | 358 | 15 |
| 13 | Johns Hopkins | 5-3 | 293 | 11 |
| 14 | UW-Whitewater | 2-2 | 261 | 13 |
| 15 | Denison | 5-1 | 242 | 22 |
| 16 | Shenandoah | 11-4 | 223 | 18 |
| 17 | Baldwin Wallace | 10-1 | 177 | rv |
| 18 | Trinity (Texas) | 6-5 | 150 | 17 |
| 19 | Adrian | 5-4 | 147 | 14 |
| 20 | Aurora | 5-3 | 142 | 16 |
| 21 | Chapman | 10-4 | 125 | 24 |
| 22 | Loras | 12-0 | 109 | rv |
| 23 | Cal Lutheran | 12-4 | 96 | 20 |
| 24 | Kean | 11-4 | 90 | 21 |
| 25 | Washington and Jefferson | 4-2 | 82 | 23 |
Dropped out: No. 19 Southern Maine, No. 25 East Texas Baptist.
Others receiving votes: Southern Maine 57, Oswego State 50, Rochester 40, Hendrix 34, Arcadia 26, William Paterson 24, Babson 19, Christopher Newport 19, East Texas Baptist 15, UW-Stevens Point 13, Berry 11, Tufts 11, Pacific Lutheran 8, Wabash 5, UW-La Crosse 4, Randolph-Macon 3, Wooster 2, Augustana 1, La Verne 1, Marymount 1, Millikin 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.