Through games of Sunday, March 20, 2022:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Marietta (24) | 12-2 | 624 | 1 |
| 2 | Birmingham-Southern | 14-4 | 562 | 3 |
| 3 | Eastern Connecticut | 8-1 | 550 | 4 |
| 4 | Lynchburg | 14-3 | 508 | 6 |
| 5 | Texas-Dallas | 17-3 | 495 | 7 |
| 6 | LaGrange (1) | 17-1 | 471 | 12 |
| 7 | Cortland | 13-6 | 466 | 2 |
| 8 | Webster | 10-3 | 463 | 10 |
| 9 | Rowan | 8-3 | 406 | 9 |
| 10 | North Central (Ill.) | 13-5 | 403 | 5 |
| 11 | Baldwin Wallace | 13-1 | 351 | 17 |
| 12 | UW-Whitewater | 5-2 | 336 | 14 |
| 13 | Salisbury | 12-7 | 290 | 8 |
| 14 | Shenandoah | 15-5 | 284 | 16 |
| 15 | Loras | 16-0 | 233 | 22 |
| 16 | Trinity (Texas) | 10-5 | 206 | 18 |
| 17 | Cal Lutheran | 14-4 | 188 | 23 |
| 18 | Denison | 8-4 | 161 | 15 |
| 19 | Aurora | 7-3 | 149 | 20 |
| 20 | Kean | 13-4 | 142 | 24 |
| 21 | Chapman | 12-5 | 124 | 21 |
| 22 | Adrian | 8-4 | 120 | 19 |
| 23 | Oswego State | 10-3 | 110 | rv |
| 24 | Johns Hopkins | 8-6 | 84 | 13 |
| 25 | Hendrix | 20-2 | 67 | rv |
Dropped out: No. 11 Wheaton (Mass.), No. 25 Washington and Jefferson
Others receiving votes: Rochester 57, Wheaton (Mass.) 38, Arcadia 35, Christopher Newport 29, Pacific Lutheran 24, UW-Stevens Point 17, Augustana 16, Marymount 14, La Verne 13, Randolph-Macon 13, Wabash 11, Wooster 10, William Paterson 9, Millikin 6, Tufts 6, Babson 5, Washington and Jefferson 4, Roger Williams 4, Bethel (Minn.) 1, East Texas Baptist 1, Ithaca 1, Mass.-Boston 1, New York University 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.