Through games of Sunday, April 17, 2022:
| # | School (1st votes) | Rec | Pts | Prev. |
| 1 | Marietta (24) | 27-3 | 624 | 1 |
| 2 | Eastern Connecticut | 22-2 | 579 | 2 |
| 3 | Birmingham-Southern | 27-7 | 546 | 4 |
| 4 | LaGrange (1) | 27-4 | 539 | 3 |
| 5 | Lynchburg | 26-6 | 499 | 5 |
| 6 | Cortland | 25-7 | 484 | 6 |
| 7 | Rowan | 21-6 | 443 | 7 |
| 8 | Salisbury | 24-7 | 417 | 10 |
| 9 | Arcadia | 28-4 | 403 | 14 |
| 10 | UW-Whitewater | 19-6 | 376 | 11 |
| 11 | Webster | 21-5 | 356 | 12 |
| 12 | North Central (Ill.) | 22-7 | 339 | 8 |
| 13 | Baldwin Wallace | 21-6 | 301 | 9 |
| 14 | Kean | 26-6 | 244 | 16 |
| 15 | Trinity (Texas) | 24-7 | 239 | 19 |
| 16 | UW-Stevens Point | 18-4 | 228 | 17 |
| 17 | Texas-Dallas | 25-7 | 223 | 13 |
| 18 | La Verne | 24-5-1 | 212 | 20 |
| 19 | Pomona-Pitzer | 24-4 | 176 | 24 |
| 20 | Oswego State | 19-6 | 159 | 21 |
| 21 | Aurora | 19-5 | 153 | 18 |
| 22 | Rochester | 24-4 | 140 | rv |
| 23 | Tufts | 17-6 | 87 | 15 |
| 24 | Shenandoah | 23-8-1 | 71 | 25 |
| 25 | Texas Lutheran | 25-7 | 46 | rv |
Dropped out: No. 22 Loras, No. 23 Chapman.
Others receiving votes: Denison 40, Chapman 39, Christopher Newport 33, Loras 33, Bethel (Minn.) 28, Endicott 16, Mass.-Boston 9, Brockport 9, Roger Williams 8, Washington & Jefferson 8, Montclair State 6, Cal Lutheran 3, Hendrix 3, Pacific Lutheran 2, Randolph-Macon 2, Skidmore 1, William Paterson 1.
The D3baseball.com Top 25 is voted on by a panel of 25 Sports Information Directors and media members from across the country, and is published weekly. Full members of NCAA Division III are eligible.